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B0.7 [p528B0.7]
B0.7 [p528B0.7]
規(guī)格:
貨期:
編號(hào):B239471
品牌:Mingzhoubio

標(biāo)準(zhǔn)菌株
定量菌液
DNA
RNA

規(guī)格:
凍干粉
斜面
甘油
平板


產(chǎn)品名稱 B0.7 [p528B0.7]
商品貨號(hào) B239471
Designations B0.7 [p528B0.7]
Species Homo sapiens, human
Depositors Temple University, CM Croce, Temple University
Applications
Has been used to detect t(1;14)(p32;q11) translocations associated with certain acute T-cell leukemias based on the size of the EcoRI fragment detected.
Vector
Construct size (kb): 3.400000095367432
Insert
DNA: genomic
Insert lengths(kb): 0.699999988079071
Tissue: acute T-lymphoblastic leukemia DU.528 cell line
Gene product: T-cell acute lymphocytic leukemia 1 (NOTE: redefinition of symbol)(T cell lymphoma 5, helix-loop-helix protein tal-1, 34 kDa) [TAL*]
Insert Size (kb) 0.700
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Comments
Restriction digests of the clone give the following sizes (kb): BamHI--2.6, .72; EcoRI--3.7; HindIII--3.7.
Derived from a germ-line fragment that includes what would be the 1p+ translocation breakpoint in the DU.528 cell line.
Detects a human genomic germline EcoRI fragment of 17.5 kb.
Has been used to detect t(1;14)(p32;q11) translocations associated with certain acute T-cell leukemias based on the size of the EcoRI fragment detected.
Detects transcripts of 5.4, 2.6, and 2.2 kb from TAL1 (TCL5).
References

Croce CM. TCL-5 gene rearrangement involved in T-cell leukemia and melanoma. US Patent 5,242,795 dated Sep 7 1993

Finger LR, et al. Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma. Proc. Natl. Acad. Sci. USA 86: 5039-5043, 1989. PubMed: 2740341

Disclosure This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC.
梅經(jīng)理 17280875617 1438578920
胡經(jīng)理 13345964880 2438244627
周經(jīng)理 17757487661 1296385441
于經(jīng)理 18067160830 2088210172
沈經(jīng)理 19548299266 2662369050
李經(jīng)理 13626845108 972239479
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